In recent years, the boiling granulator has been widely used in the pharmaceutical industry, especially the application of granulation and coating, but from the GMP and solid preparation process requirements: the original boiling granulator exposed some urgent need to improve the problem before In line with the current pharmaceutical process requirements. This article analyzes the above problems and the requirements of the structure of the new explosion-proof pellet coating machine. The purpose is to push the boiling granulation coating process to a new high.

With the increasing demand for pharmaceutical machinery from the pharmaceutical industry and GMP requirements, the original FL type boiling granulator gradually exposed some problems in the production process. These problems are no longer applicable in the application of granulation coating process, and its performance In the following points:
(1) The explosion-proof performance of the equipment is poor, but only simple explosion-proof measures are adopted, which can not ensure the safety of the operator and the plant, and there is a certain hidden danger in the production;
(2) Disassembly and assembly of the bag is inconvenient. Although the wire rope structure is used for disassembling the cloth bag, the connection between the cloth bag and the upper cylinder needs to artificially fix the bottom edge of the cloth bag and the upper cylinder body flange with a rope. Convenience;
(3) The fluidized bed of the fluidized bed adopts vertical perforated plates or mat-shaped reticular plates. The problems such as uneven fluidization or dead angle are easily caused during the fluidization process of the materials, and the uniform distribution of the drugs in the granules cannot be ensured. degree;
(4) The fluidized plates and the granulation containers are often fixed by bolts, which are inconvenient to dismantle, which can easily result in unclean cleaning, resulting in problems such as residues of drugs;
(5) In the process of granulation, loose particles, low strength, and low bulk density, when the top spray is used for fluidized coating of particles, the coating rate is low. And these existing problems make the boiling granulator unable to meet the pharmaceutical industry's GMP requirements for pharmaceutical machines.

In response to the above problems, according to the production experience of the production of boiling granulator over the years and the characteristics of similar foreign equipment, Changzhou Pilot Drying Equipment Co., Ltd. developed a new type of explosion-proof granulation coating machine and introduced it to the market. The equipment has granulation, coating, drying function and explosion-proof performance. It is suitable for the surface coating of flour and granules, powders, granules and pellets in the Chinese and western medicine, food, chemical industry and other industries.